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NF kappa B regulator Bcl3 controls development and function of classical dendritic cells required for resistance to Toxoplasma gondii

The atypical IκB family member Bcl3 associates with p50/NF-κB1 or p52/NF-κB2 homodimers in the nucleus, and positively or negatively modulates transcription in a context-dependent manner. In mice lacking Bcl3 globally or specifically in CD11c(+) cells, we previously reported that Toxoplasma gondii i...

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Detalles Bibliográficos
Autores principales: Guha, June, Kang, Byunghyun, Claudio, Estefania, Redekar, Neelam R., Wang, Hongshan, Kelsall, Brian L., Siebenlist, Ulrich, Murphy, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651595/
https://www.ncbi.nlm.nih.gov/pubmed/36318581
http://dx.doi.org/10.1371/journal.ppat.1010502