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Stress-induced reduction of Na(+)/H(+) exchanger isoform 1 promotes maladaptation of neuroplasticity and exacerbates depressive behaviors

Major depression disorder (MDD) is a neuropsychiatric disorder characterized by abnormal neuronal activity in specific brain regions. A factor that is crucial in maintaining normal neuronal functioning is intracellular pH (pHi) homeostasis. In this study, we show that chronic stress, which induces d...

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Detalles Bibliográficos
Autores principales: Li, Ye, Fan, Cuiqin, Wang, Changmin, Wang, Liyan, Yi, Yuhang, Mao, Xueqin, Chen, Xiao, Lan, Tian, Wang, Wenjing, Yu, Shu Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651740/
https://www.ncbi.nlm.nih.gov/pubmed/36367929
http://dx.doi.org/10.1126/sciadv.add7063