Inhibited KdpFABC transitions into an E1 off-cycle state

KdpFABC is a high-affinity prokaryotic K(+) uptake system that forms a functional chimera between a channel-like subunit (KdpA) and a P-type ATPase (KdpB). At high K(+) levels, KdpFABC needs to be inhibited to prevent excessive K(+) accumulation to the point of toxicity. This is achieved by a phosph...

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Detalles Bibliográficos
Autores principales: Silberberg, Jakob M, Stock, Charlott, Hielkema, Lisa, Corey, Robin A, Rheinberger, Jan, Wunnicke, Dorith, Dubach, Victor RA, Stansfeld, Phillip J, Hänelt, Inga, Paulino, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651954/
https://www.ncbi.nlm.nih.gov/pubmed/36255052
http://dx.doi.org/10.7554/eLife.80988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651954/
https://www.ncbi.nlm.nih.gov/pubmed/36255052
http://dx.doi.org/10.7554/eLife.80988

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