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Inhibited KdpFABC transitions into an E1 off-cycle state
KdpFABC is a high-affinity prokaryotic K(+) uptake system that forms a functional chimera between a channel-like subunit (KdpA) and a P-type ATPase (KdpB). At high K(+) levels, KdpFABC needs to be inhibited to prevent excessive K(+) accumulation to the point of toxicity. This is achieved by a phosph...
Autores principales: | Silberberg, Jakob M, Stock, Charlott, Hielkema, Lisa, Corey, Robin A, Rheinberger, Jan, Wunnicke, Dorith, Dubach, Victor RA, Stansfeld, Phillip J, Hänelt, Inga, Paulino, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651954/ https://www.ncbi.nlm.nih.gov/pubmed/36255052 http://dx.doi.org/10.7554/eLife.80988 |
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