Metformin Suppresses Hepatocellular Carcinoma through Regulating Alternative Splicing of LGR4

METHODS: First, the expression of LGR4 in HCC tumor tissues and cell lines was detected by western blotting and immunofluorescence. The ability of cell proliferation, migration, and invasion was detected with CCK8, wound-healing, and transwell assays when overexpressing LGR4 or treating with metform...

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Detalles Bibliográficos
Autores principales: Zhuo, Han, Miao, Shuying, Jin, Zhenquan, Zhu, Deming, Xu, Zhenggang, Sun, Dongwei, Ji, Jie, Tan, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652085/
https://www.ncbi.nlm.nih.gov/pubmed/36385965
http://dx.doi.org/10.1155/2022/1774095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652085/
https://www.ncbi.nlm.nih.gov/pubmed/36385965
http://dx.doi.org/10.1155/2022/1774095

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