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Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals

CD147 is an immunoglobulin-like receptor that is highly expressed in various cancers and involved in the growth, metastasis, and activation of inflammatory pathways via interactions with various functional molecules, such as integrins, CD44, and monocarboxylate transporters. Through screening of CD1...

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Detalles Bibliográficos
Autores principales: Fukuchi, Keisuke, Nanai, Kayoko, Yuita, Hiroshi, Maru, Chikako, Tsukada, Jun, Ishigami, Masato, Nagai, Yoko, Nakano, Yoko, Yoshimura, Chigusa, Yoneda, Kozo, Amano, Masato, Nakamura, Kensuke, Oda, Yoko, Nishigohri, Haruyuki, Yamamoto, Shoji, Ohnishi-Totoki, Yusuke, Inaki, Koichiro, Komori, Hironobu, Nakano, Rika, Kanari, Yoshiyuki, Nishida, Atsuko, Matsui, Yumi, Funo, Satoko, Takahashi, Sayako, Ohtsuka, Toshiaki, Agatsuma, Toshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652086/
https://www.ncbi.nlm.nih.gov/pubmed/36385956
http://dx.doi.org/10.1155/2022/3552793