Cargando…

Development of microglia-targeting adeno-associated viral vectors as tools to study microglial behavior in vivo

Here we describe the microglia-targeting adeno-associated viral (AAV) vectors containing a 1.7-kb putative promoter region of microglia/macrophage-specific ionized calcium-binding adaptor molecule 1 (Iba1), along with repeated miRNA target sites for microRNA (miR)-9 and miR-129-2-3p. The 1.7-kb geno...

Descripción completa

Detalles Bibliográficos
Autores principales: Okada, Yukihiro, Hosoi, Nobutake, Matsuzaki, Yasunori, Fukai, Yuuki, Hiraga, Akito, Nakai, Junichi, Nitta, Keisuke, Shinohara, Yoichiro, Konno, Ayumu, Hirai, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652230/
https://www.ncbi.nlm.nih.gov/pubmed/36369525
http://dx.doi.org/10.1038/s42003-022-04200-3