Cargando…
Development of microglia-targeting adeno-associated viral vectors as tools to study microglial behavior in vivo
Here we describe the microglia-targeting adeno-associated viral (AAV) vectors containing a 1.7-kb putative promoter region of microglia/macrophage-specific ionized calcium-binding adaptor molecule 1 (Iba1), along with repeated miRNA target sites for microRNA (miR)-9 and miR-129-2-3p. The 1.7-kb geno...
Autores principales: | Okada, Yukihiro, Hosoi, Nobutake, Matsuzaki, Yasunori, Fukai, Yuuki, Hiraga, Akito, Nakai, Junichi, Nitta, Keisuke, Shinohara, Yoichiro, Konno, Ayumu, Hirai, Hirokazu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652230/ https://www.ncbi.nlm.nih.gov/pubmed/36369525 http://dx.doi.org/10.1038/s42003-022-04200-3 |
Ejemplares similares
-
GABAergic neuron-specific whole-brain transduction by AAV-PHP.B incorporated with a new GAD65 promoter
por: Hoshino, Chiaki, et al.
Publicado: (2021) -
Viral Vector-Based Dissection of Marmoset GFAP Promoter in Mouse and Marmoset Brains
por: Shinohara, Yoichiro, et al.
Publicado: (2016) -
Minimal Purkinje Cell-Specific PCP2/L7 Promoter Virally Available for Rodents and Non-human Primates
por: Nitta, Keisuke, et al.
Publicado: (2017) -
Protein kinase Cγ in cerebellar Purkinje cells regulates Ca(2+)-activated large-conductance K(+) channels and motor coordination
por: Watanave, Masashi, et al.
Publicado: (2022) -
A blood-brain barrier-penetrating AAV2 mutant created by a brain microvasculature endothelial cell-targeted AAV2 variant
por: Kawabata, Hayato, et al.
Publicado: (2023)