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Design and directed evolution of noncanonical β-stereoselective metalloglycosidases
Metallohydrolases are ubiquitous in nearly all subclasses of hydrolases, utilizing metal elements to activate a water molecule and facilitate its subsequent dissociation of diverse chemical bonds. However, such a catalytic role of metal ions is rarely found with glycosidases that hydrolyze the glyco...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652281/ https://www.ncbi.nlm.nih.gov/pubmed/36369431 http://dx.doi.org/10.1038/s41467-022-34713-8 |