CRISPR FISHer enables high-sensitivity imaging of nonrepetitive DNA in living cells through phase separation-mediated signal amplification

The dynamic three-dimensional structures of chromatin and extrachromosomal DNA molecules regulate fundamental cellular processes and beyond. However, the visualization of specific DNA sequences in live cells, especially nonrepetitive sequences accounting for most of the genome, is still vastly chall...

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Detalles Bibliográficos
Autores principales: Lyu, Xin-Yuan, Deng, Yuan, Huang, Xiao-Yan, Li, Zhen-Zhen, Fang, Guo-Qing, Yang, Dong, Wang, Feng-Liu, Kang, Wang, Shen, En-Zhi, Song, Chun-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652286/
https://www.ncbi.nlm.nih.gov/pubmed/36104507
http://dx.doi.org/10.1038/s41422-022-00712-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652286/
https://www.ncbi.nlm.nih.gov/pubmed/36104507
http://dx.doi.org/10.1038/s41422-022-00712-z

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