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Decreased PPARgamma in the trigeminal spinal subnucleus caudalis due to neonatal injury contributes to incision-induced mechanical allodynia in female rats

Whisker pad skin incision in infancy causes the prolongation of mechanical allodynia after re-incision in adulthood. A recent study also proposed the importance of sex differences in pain signaling in the spinal cord. However, the sex difference in re-incision-induced mechanical allodynia in the oro...

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Detalles Bibliográficos
Autores principales: Otsuji, Jo, Hayashi, Yoshinori, Hitomi, Suzuro, Soma, Chihiro, Soma, Kumi, Shibuta, Ikuko, Iwata, Koichi, Shirakawa, Tetsuo, Shinoda, Masamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652333/
https://www.ncbi.nlm.nih.gov/pubmed/36369249
http://dx.doi.org/10.1038/s41598-022-23832-3