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A critical bioenergetic switch is regulated by IGF2 during murine cartilage development

Long bone growth requires the precise control of chondrocyte maturation from proliferation to hypertrophy during endochondral ossification, but the bioenergetic program that ensures normal cartilage development is still largely elusive. We show that chondrocytes have unique glucose metabolism signat...

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Detalles Bibliográficos
Autores principales: Hollander, Judith M., Li, Lingyun, Rawal, Miraj, Wang, Si Kun, Shu, Yue, Zhang, Ming, Nielsen, Heber C., Rosen, Clifford J., Zeng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652369/
https://www.ncbi.nlm.nih.gov/pubmed/36369360
http://dx.doi.org/10.1038/s42003-022-04156-4