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A critical bioenergetic switch is regulated by IGF2 during murine cartilage development
Long bone growth requires the precise control of chondrocyte maturation from proliferation to hypertrophy during endochondral ossification, but the bioenergetic program that ensures normal cartilage development is still largely elusive. We show that chondrocytes have unique glucose metabolism signat...
Autores principales: | Hollander, Judith M., Li, Lingyun, Rawal, Miraj, Wang, Si Kun, Shu, Yue, Zhang, Ming, Nielsen, Heber C., Rosen, Clifford J., Zeng, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652369/ https://www.ncbi.nlm.nih.gov/pubmed/36369360 http://dx.doi.org/10.1038/s42003-022-04156-4 |
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