Oxidative stress mediates end-organ damage in a novel model of acetaminophen-toxicity in Drosophila

Acetaminophen is the most common cause of acute drug-induced liver injury in the United States. However, research into the mechanisms of acetaminophen toxicity and the development of novel therapeutics is hampered by the lack of robust, reproducible, and cost-effective model systems. Herein, we char...

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Detalles Bibliográficos
Autores principales: Saeedi, Bejan J., Hunter-Chang, Sarah, Luo, Liping, Li, Kaiyan, Liu, Ken H., Robinson, Brian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652370/
https://www.ncbi.nlm.nih.gov/pubmed/36369211
http://dx.doi.org/10.1038/s41598-022-21156-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652370/
https://www.ncbi.nlm.nih.gov/pubmed/36369211
http://dx.doi.org/10.1038/s41598-022-21156-w

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