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Ensemble machine learning identifies genetic loci associated with future worsening of disability in people with multiple sclerosis

Limited studies have been conducted to identify and validate multiple sclerosis (MS) genetic loci associated with disability progression. We aimed to identify MS genetic loci associated with worsening of disability over time, and to develop and validate ensemble genetic learning model(s) to identify...

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Detalles Bibliográficos
Autores principales: Fuh-Ngwa, Valery, Zhou, Yuan, Melton, Phillip E., van der Mei, Ingrid, Charlesworth, Jac C., Lin, Xin, Zarghami, Amin, Broadley, Simon A., Ponsonby, Anne-Louise, Simpson-Yap, Steve, Lechner-Scott, Jeannette, Taylor, Bruce V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652373/
https://www.ncbi.nlm.nih.gov/pubmed/36369345
http://dx.doi.org/10.1038/s41598-022-23685-w