Safety evaluations of a synthetic antimicrobial peptide administered intravenously in rats and dogs

The antimicrobial peptide SET-M33 is under study for the development of a new antibiotic against major Gram-negative pathogens. Here we report the toxicological evaluation of SET-M33 administered intravenously to rats and dogs. Dose range finding experiments determined the doses to use in toxicokine...

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Detalles Bibliográficos
Autores principales: Cresti, Laura, Falciani, Chiara, Cappello, Giovanni, Brunetti, Jlenia, Vailati, Silvia, Melloni, Elsa, Bracci, Luisa, Pini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652379/
https://www.ncbi.nlm.nih.gov/pubmed/36369523
http://dx.doi.org/10.1038/s41598-022-23841-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652379/
https://www.ncbi.nlm.nih.gov/pubmed/36369523
http://dx.doi.org/10.1038/s41598-022-23841-2

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