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Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology

Cognitive deficits are known to be related to most forms of psychopathology. Here, we perform local genetic correlation analysis as a means of identifying independent segments of the genome that show biologically interpretable pleiotropic associations between cognitive dimensions and psychopathology...

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Detalles Bibliográficos
Autores principales: Lam, Max, Chen, Chia-Yen, Hill, W. David, Xia, Charley, Tian, Ruoyu, Levey, Daniel F., Gelernter, Joel, Stein, Murray B., Hatoum, Alexander S., Huang, Hailiang, Malhotra, Anil K., Runz, Heiko, Ge, Tian, Lencz, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652380/
https://www.ncbi.nlm.nih.gov/pubmed/36369282
http://dx.doi.org/10.1038/s41467-022-34418-y