Catalytic DxD motif caged in Asx-turn and Met–aromatic interaction attenuates the pathogenic glycosylation of SseK2/NleB2 effectors

Pathogenic bacteria encode virulent glycosyltransferases that conjugate various glycans onto host crucial proteins, which allows adhesion to mammalian cells and modulates host cellular processes for pathogenesis. Escherichia coli NleB1, Citrobacter rodentium NleB, and Salmonella enterica SseK1/3 typ...

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Detalles Bibliográficos
Autores principales: Koh, Eunhee, Kim, Uijin, Cho, Hyun-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652389/
https://www.ncbi.nlm.nih.gov/pubmed/36369343
http://dx.doi.org/10.1038/s41598-022-22803-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652389/
https://www.ncbi.nlm.nih.gov/pubmed/36369343
http://dx.doi.org/10.1038/s41598-022-22803-y

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