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Application of multi-objective optimization in the study of anti-breast cancer candidate drugs

In the development of anti-breast cancer drugs, the quantitative structure-activity relationship model of compounds is usually used to select potential active compounds. However, the existing methods often have problems such as low model prediction performance, lack of overall consideration of the b...

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Detalles Bibliográficos
Autores principales: Mei, Yuan, Wu, Kaijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652409/
https://www.ncbi.nlm.nih.gov/pubmed/36369522
http://dx.doi.org/10.1038/s41598-022-23851-0