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Enantioselective synthesis of N-alkylindoles enabled by nickel-catalyzed C-C coupling

Enantioenriched N-alkylindole compounds, in which nitrogen is bound to a stereogenic sp(3) carbon, are an important entity of target molecules in the fields of biological, medicinal, and organic chemistry. Despite considerable efforts aimed at inventing methods for stereoselective indole functionali...

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Detalles Bibliográficos
Autores principales: Li, Lun, Ren, Jiangtao, Zhou, Jingjie, Wu, Xiaomei, Shao, Zhihui, Yang, Xiaodong, Qian, Deyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652415/
https://www.ncbi.nlm.nih.gov/pubmed/36369422
http://dx.doi.org/10.1038/s41467-022-34615-9