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Population pharmacokinetics of everolimus in adult liver transplant patients: Comparison to tacrolimus disposition and extrapolation to pediatrics

Everolimus has recently been used to prevent graft rejection in liver transplantation and reduces the incidence of kidney dysfunction caused by calcineurin inhibitors. In this study, a population pharmacokinetic analysis was conducted to improve the individualization of everolimus therapy. Japanese...

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Detalles Bibliográficos
Autores principales: Itohara, Kotaro, Yano, Ikuko, Nakagawa, Shunsaku, Sugimoto, Mitsuhiro, Hirai, Machiko, Yonezawa, Atsushi, Imai, Satoshi, Nakagawa, Takayuki, Hira, Daiki, Ito, Takashi, Hata, Koichiro, Hatano, Etsuro, Terada, Tomohiro, Matsubara, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652441/
https://www.ncbi.nlm.nih.gov/pubmed/36004935
http://dx.doi.org/10.1111/cts.13389