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Genomewide association study identifies a novel variant associated with tacrolimus trough concentration in Chinese renal transplant recipients

Tacrolimus (TAC) is an immunosuppressant widely used in kidney transplantation. TAC displays considerable interindividual variability in pharmacokinetics (PKs). Genetic and clinical factors play important roles in TAC PKs. We enrolled a total of 251 Chinese renal transplant recipients and conducted...

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Detalles Bibliográficos
Autores principales: Yang, Siyao, Jiang, Haixia, Li, Chengcheng, Lu, Huijie, Li, Chuanjiang, Ye, Demei, Qi, Huana, Xu, Wenbin, Bao, Xiaojie, Maseko, Nicola, Zhang, Siqi, Shao, Ruifan, Li, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652447/
https://www.ncbi.nlm.nih.gov/pubmed/35977080
http://dx.doi.org/10.1111/cts.13388