Cargando…

Genomewide association study identifies a novel variant associated with tacrolimus trough concentration in Chinese renal transplant recipients

Tacrolimus (TAC) is an immunosuppressant widely used in kidney transplantation. TAC displays considerable interindividual variability in pharmacokinetics (PKs). Genetic and clinical factors play important roles in TAC PKs. We enrolled a total of 251 Chinese renal transplant recipients and conducted...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Siyao, Jiang, Haixia, Li, Chengcheng, Lu, Huijie, Li, Chuanjiang, Ye, Demei, Qi, Huana, Xu, Wenbin, Bao, Xiaojie, Maseko, Nicola, Zhang, Siqi, Shao, Ruifan, Li, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652447/ https://www.ncbi.nlm.nih.gov/pubmed/35977080 http://dx.doi.org/10.1111/cts.13388

Ejemplares similares

Tacrolimus trough levels in kidney transplant recipients
por: Hwang, Young Hui, et al.
Publicado: (2021)

Evaluation of clotrimazole prophylaxis on tacrolimus trough concentrations in kidney transplant recipients
por: Wings, Emily, et al.
Publicado: (2022)

Plasma metabolomic profiling reveals factors associated with dose-adjusted trough concentration of tacrolimus in liver transplant recipients
por: Zhu, Huaijun, et al.
Publicado: (2022)

Pantoprazole Does not Affect Serum Trough Levels of Tacrolimus and Everolimus in Liver Transplant Recipients
por: Bremer, Sebastian C. B., et al.
Publicado: (2018)

Number of Regularly Prescribed Drugs and Intrapatient Tacrolimus Trough Levels Variability in Stable Kidney Transplant Recipients
por: Giza, Piotr, et al.
Publicado: (2020)

Identification of Antibiotic Administration as a Potentially Novel Factor Associated With Tacrolimus Trough Variability in Kidney Transplant Recipients: A Preliminary Study
por: Zheng, YuanPu, et al.
Publicado: (2019)

Variability of Tacrolimus Trough Concentration in Liver Transplant Patients: Which Role of Inflammation?
por: Chavant, Anaelle, et al.
Publicado: (2021)

Manic-Like Psychosis Associated with Elevated Trough Tacrolimus Blood Concentrations 17 Years after Kidney Transplant
por: Bersani, Giuseppe, et al.
Publicado: (2013)

Genomewide Association Studies in Pharmacogenomics
por: McInnes, Gregory, et al.
Publicado: (2021)

The influence of recipient SLCO1B1 rs2291075 polymorphism on tacrolimus dose–corrected trough concentration in the early period after liver transplantation
por: Wu, Yi, et al.
Publicado: (2021)

Mycophenolic Acid Trough Concentration and Dose Are Associated with Hematologic Abnormalities but Not Rejection in Kidney Transplant Recipients
por: Jung, Hee-Yeon, et al.
Publicado: (2020)

Genomewide Association Study of Simvastatin Pharmacokinetics
por: Mykkänen, Anssi J. H., et al.
Publicado: (2022)

Does the Tacrolimus Trough Level Adequately Predict Drug Exposure in Patients Requiring a High Tacrolimus Dose?
por: Haverals, Lien, et al.
Publicado: (2023)

The Association of Tacrolimus Formulation Switching with Trough Concentration Variability: A Retrospective Cohort Study of Tacrolimus Use Post-Kidney Transplantation Based on National Drug Code (NDC) Numbers
por: Schwartz, Jason J., et al.
Publicado: (2019)

The earliest trough concentration predicts the dose of tacrolimus required for remission induction therapy in ulcerative colitis patients
por: Hiraoka, Sakiko, et al.
Publicado: (2015)

Prediction of Tacrolimus Dose/Weight-Adjusted Trough Concentration in Pediatric Refractory Nephrotic Syndrome: A Machine Learning Approach
por: Mo, Xiaolan, et al.
Publicado: (2022)

Tacrolimus trough levels higher than 6 ng/mL might not be required after a year in stable kidney transplant recipients
por: Jung, Hee-Yeon, et al.
Publicado: (2020)

Estimation of significance thresholds for genomewide association scans
por: Dudbridge, Frank, et al.
Publicado: (2008)

Transethnic Meta-Analysis of Genomewide Association Studies
por: Morris, Andrew P
Publicado: (2011)

METAL: fast and efficient meta-analysis of genomewide association scans
por: Willer, Cristen J., et al.
Publicado: (2010)

A Novel, Dose-Adjusted Tacrolimus Trough-Concentration Model for Predicting and Estimating Variance After Kidney Transplantation
por: Kim, Janet, et al.
Publicado: (2019)

Effects of Wuzhi Capsules on Blood Concentration of Tacrolimus in Renal Transplant Recipients
por: Yan, Lin, et al.
Publicado: (2019)

Predictors of Adverse Events and Determinants of the Voriconazole Trough Concentration in Kidney Transplantation Recipients
por: Zhao, Yi‐Chang, et al.
Publicado: (2020)

Long-Term Tacrolimus Blood Trough Level and Patient Survival in Adult Liver Transplantation
por: Hsiao, Chih-Yang, et al.
Publicado: (2021)

Effects of ABCB1 DNA methylation in donors on tacrolimus blood concentrations in recipients following liver transplantation
por: Shi, Chengcheng, et al.
Publicado: (2022)

Variation in Tacrolimus Trough Concentrations in Liver Transplant Patients Undergoing Endoscopic Retrograde Cholangiopancreatography: A Retrospective, Observational Study
por: Wang, Rongrong, et al.
Publicado: (2020)

Monitoring Tacrolimus Trough Concentrations During the First Year After Kidney Transplantation: A National Retrospective Cohort Study
por: Alghanem, Sarah S., et al.
Publicado: (2020)

Genomewide association study for onset age in Parkinson disease
por: Latourelle, Jeanne C, et al.
Publicado: (2009)

Genomewide landscape of gene–metabolome associations in Escherichia coli
por: Fuhrer, Tobias, et al.
Publicado: (2017)

Tacrolimus Levels Are Not Associated with Risk of Malignancy in Lung Transplant Recipients
por: Fox, Benjamin Daniel, et al.
Publicado: (2017)

Body composition is associated with tacrolimus pharmacokinetics in kidney transplant recipients
por: Francke, M. I., et al.
Publicado: (2022)

Higher tacrolimus trough levels and time in the therapeutic range are associated with the risk of acute rejection in the first month after renal transplantation
por: Nguyen, Thi Van Anh, et al.
Publicado: (2023)

Flucloxacillin decreases tacrolimus blood trough levels: a single-center retrospective cohort study
por: Veenhof, Herman, et al.
Publicado: (2020)

Genomewide characterization of non-polyadenylated RNAs
por: Yang, Li, et al.
Publicado: (2011)

Association Between Trough Level of Tacrolimus and Change in Estimated Glomerular Filtration Rate 1 Year After Living Donor Liver Transplantation
por: Muta, Kumiko, et al.
Publicado: (2021)

The Nature of Nurture: A Genomewide Association Scan for Family Chaos
por: Butcher, Lee M., et al.
Publicado: (2008)

Genomewide Association Scan of Suicidal Thoughts and Behaviour in Major Depression
por: Schosser, Alexandra, et al.
Publicado: (2011)

PW01-038 – Genomewide association study of Still’s disease
por: Ombrello, MJ, et al.
Publicado: (2013)

Gene-based Genomewide Association Analysis: A Comparison Study
por: Kang, Guolian, et al.
Publicado: (2013)

FarmCPUpp: Efficient large‐scale genomewide association studies
por: Kusmec, Aaron, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_52cp6ggu7i358nc9a5o86spunp