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The ischaemic preconditioning paradox and its implications for islet isolation from heart-beating and non heart-beating donors

The impact of ischaemia can severely damage procured donor organs for transplantation. The pancreas, and pancreatic islets in particular, is one of the most sensitive tissues towards hypoxia. The present study was aimed to assess the effect of hypoxic preconditioning (HP) performed ex-vivo in islets...

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Detalles Bibliográficos
Autores principales: Brandhorst, Daniel, Brandhorst, Heide, Acreman, Samuel, Johnson, Paul R. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652462/
https://www.ncbi.nlm.nih.gov/pubmed/36369239
http://dx.doi.org/10.1038/s41598-022-23862-x