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The ischaemic preconditioning paradox and its implications for islet isolation from heart-beating and non heart-beating donors
The impact of ischaemia can severely damage procured donor organs for transplantation. The pancreas, and pancreatic islets in particular, is one of the most sensitive tissues towards hypoxia. The present study was aimed to assess the effect of hypoxic preconditioning (HP) performed ex-vivo in islets...
Autores principales: | Brandhorst, Daniel, Brandhorst, Heide, Acreman, Samuel, Johnson, Paul R. V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652462/ https://www.ncbi.nlm.nih.gov/pubmed/36369239 http://dx.doi.org/10.1038/s41598-022-23862-x |
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