Cargando…

Landscape of potentially targetable receptor tyrosine kinase fusions in diverse cancers by DNA-based profiling

Recurrent fusions of receptor tyrosine kinases (RTKs) are often driving events in tumorigenesis that carry important diagnostic value and are potentially targetable by the increasing number of tyrosine kinase inhibitors (TKIs). Here, we characterized the spectrum of 1324 RTK fusions with intact kina...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tiantian, Wei, Li, Lu, Qiang, Shao, Yanmei, You, Shuqing, Yin, Jiani C., Wang, Sha, Shao, Yang, Chen, Zhanhong, Wang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652465/
https://www.ncbi.nlm.nih.gov/pubmed/36369474
http://dx.doi.org/10.1038/s41698-022-00325-0