Cargando…
Landscape of potentially targetable receptor tyrosine kinase fusions in diverse cancers by DNA-based profiling
Recurrent fusions of receptor tyrosine kinases (RTKs) are often driving events in tumorigenesis that carry important diagnostic value and are potentially targetable by the increasing number of tyrosine kinase inhibitors (TKIs). Here, we characterized the spectrum of 1324 RTK fusions with intact kina...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652465/ https://www.ncbi.nlm.nih.gov/pubmed/36369474 http://dx.doi.org/10.1038/s41698-022-00325-0 |