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The propofol-induced mitochondrial damage in fetal rat hippocampal neurons via the AMPK/P53 signaling pathway

BACKGROUND: Propofol is a commonly used general anesthetic that may cause neuronal damage, especially in infants and young children. Mitochondria play an essential role in cellular metabolism and signal transduction. Propofol may cause neurotoxicity by inhibiting mitochondrial function, but the mech...

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Detalles Bibliográficos
Autores principales: Xiao, Fei, Qin, Yi, Chen, Jing, Li, Chunlai, Qin, Yinying, Wei, Yi, Xie, Yubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652519/
https://www.ncbi.nlm.nih.gov/pubmed/36388781
http://dx.doi.org/10.21037/atm-22-4374