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Combined electronic medical records and gene polymorphism characteristics to establish an anti-tuberculosis drug-induced hepatic injury (ATDH) prediction model and evaluate the prediction value

BACKGROUND: Anti-tuberculosis drug-induced hepatic injury (ATDH) lacks specific diagnostic markers. The characteristics of gene polymorphisms have been preliminarily used for the risk classification of ATDH, and the activation of Pregnane X receptor/aminole-vulinic synthase-1/forkhead box O1 (PXR/AL...

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Detalles Bibliográficos
Autores principales: Zhang, Jingwei, Zhou, Wei, Ma, Shijie, Kang, Yuwei, Yang, Wei, Peng, Xiaodong, Zhou, Yi, Deng, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652536/
https://www.ncbi.nlm.nih.gov/pubmed/36388795
http://dx.doi.org/10.21037/atm-22-4551