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Atorvastatin alleviates oxidative damage by activating the nuclear factor erythroid 2-related factor 2 pathway after brain ischemia in mice

BACKGROUND: Exploring anti-oxidative stress drugs are essential to prevent and treat ischemic cerebral infarction. The present study was designed to explore the antioxidant molecular mechanism of atorvastatin underlying ischemic cerebral infarction. METHODS: Male, Nrf2+/+ and Nrf2−/− mice were subje...

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Detalles Bibliográficos
Autores principales: Fan, Jingyi, Zhang, Xiangjian, Chen, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652567/
https://www.ncbi.nlm.nih.gov/pubmed/36388806
http://dx.doi.org/10.21037/atm-22-4565