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The recycling of AMPA receptors/GABAa receptors is related to neuronal excitation/inhibition imbalance and may be regulated by KIF5A

BACKGROUND: Excitation/inhibition imbalance (E/I imbalance), which involves an increase of alpha-amino-3-hydroxy-5-methyl-4-isoxazole (AMPA) receptors (AMPARs) and decrease of gamma-aminobutyric acid type A (GABA) type A receptors (GABAaRs) on the neuron surface, has been documented in the pathogene...

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Detalles Bibliográficos
Autores principales: Li, Sijun, Huang, Hongmi, Wei, Xin, Ye, Lin, Ma, Meigang, Ling, Min, Wu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652568/
https://www.ncbi.nlm.nih.gov/pubmed/36388788
http://dx.doi.org/10.21037/atm-22-4337