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FABP4-mediated lipid droplet formation in Streptococcus uberis-infected macrophages supports host defence

Foamy macrophages containing prominent cytoplasmic lipid droplets (LDs) are found in a variety of infectious diseases. However, their role in Streptococcus uberis-induced mastitis is unknown. Herein, we report that S. uberis infection enhances the fatty acid synthesis pathway in macrophages, resulti...

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Detalles Bibliográficos
Autores principales: Wan, Zhixin, Fu, Shaodong, Wang, Zhenglei, Xu, Yuanyuan, Zhou, Yuanyuan, Lin, Xinguang, Lan, Riguo, Han, Xiangan, Luo, Zhenhua, Miao, Jinfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652580/
https://www.ncbi.nlm.nih.gov/pubmed/36371263
http://dx.doi.org/10.1186/s13567-022-01114-0