YAP/TAZ Mediate TGFβ2-Induced Schlemm's Canal Cell Dysfunction

PURPOSE: Elevated transforming growth factor beta2 (TGFβ2) levels in the aqueous humor have been linked to glaucomatous outflow tissue dysfunction. Potential mediators of dysfunction are the transcriptional coactivators, Yes-associated protein (YAP) and transcriptional coactivator with PDZ binding m...

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Detalles Bibliográficos
Autores principales: Li, Haiyan, Singh, Ayushi, Perkumas, Kristin M., Stamer, W. Daniel, Ganapathy, Preethi S., Herberg, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652721/
https://www.ncbi.nlm.nih.gov/pubmed/36350617
http://dx.doi.org/10.1167/iovs.63.12.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652721/
https://www.ncbi.nlm.nih.gov/pubmed/36350617
http://dx.doi.org/10.1167/iovs.63.12.15

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