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YAP/TAZ Mediate TGFβ2-Induced Schlemm's Canal Cell Dysfunction
PURPOSE: Elevated transforming growth factor beta2 (TGFβ2) levels in the aqueous humor have been linked to glaucomatous outflow tissue dysfunction. Potential mediators of dysfunction are the transcriptional coactivators, Yes-associated protein (YAP) and transcriptional coactivator with PDZ binding m...
Autores principales: | Li, Haiyan, Singh, Ayushi, Perkumas, Kristin M., Stamer, W. Daniel, Ganapathy, Preethi S., Herberg, Samuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652721/ https://www.ncbi.nlm.nih.gov/pubmed/36350617 http://dx.doi.org/10.1167/iovs.63.12.15 |
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