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Validation and application of a quantitative LC-MS/MS assay for the analysis of first-line anti-tuberculosis drugs, rifabutin and their metabolites in human breast milk

Breast milk is the preferred method of infant nutrition. Breastfeeding infants born to mothers treated for TB may be at risk of drug toxicity through breast milk exposure, or potentially be vulnerable to select for drug resistance with low level drug exposure. Except for isoniazid, the quantificatio...

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Detalles Bibliográficos
Autores principales: Zuma, Phiwe, Joubert, Anton, van der Merwe, Marthinus, Norman, Jennifer, Waitt, Catriona, Court, Richard, Loveday, Marian, Castel, Sandra, Wiesner, Lubbe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652742/
https://www.ncbi.nlm.nih.gov/pubmed/36215877
http://dx.doi.org/10.1016/j.jchromb.2022.123489