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Lipid saturation induces degradation of squalene epoxidase for sterol homeostasis and cell survival

A fluid membrane containing a mix of unsaturated and saturated lipids is essential for life. However, it is unclear how lipid saturation might affect lipid homeostasis, membrane-associated proteins, and membrane organelles. Here, we generate temperature-sensitive mutants of the sole fatty acid desat...

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Detalles Bibliográficos
Autores principales: Huang, Leng-Jie, Chen, Rey-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652772/
https://www.ncbi.nlm.nih.gov/pubmed/36368908
http://dx.doi.org/10.26508/lsa.202201612