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Lipid saturation induces degradation of squalene epoxidase for sterol homeostasis and cell survival
A fluid membrane containing a mix of unsaturated and saturated lipids is essential for life. However, it is unclear how lipid saturation might affect lipid homeostasis, membrane-associated proteins, and membrane organelles. Here, we generate temperature-sensitive mutants of the sole fatty acid desat...
Autores principales: | Huang, Leng-Jie, Chen, Rey-Huei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652772/ https://www.ncbi.nlm.nih.gov/pubmed/36368908 http://dx.doi.org/10.26508/lsa.202201612 |
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