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Celastrol elicits antitumor effects by inhibiting the STAT3 pathway through ROS accumulation in non-small cell lung cancer

BACKGROUND: Non-small cell lung cancer (NSCLC) is the most common lung cancer with high mortality across the world, but it is challenging to develop an effective therapy for NSCLC. Celastrol is a natural bioactive compound, which has been found to possess potential antitumor activity. However, the u...

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Detalles Bibliográficos
Autores principales: Zhao, Zhucheng, Wang, Yanmao, Gong, Yuyan, Wang, Xian, Zhang, Luyao, Zhao, Haiyang, Li, Jifa, Zhu, Jiandong, Huang, Xiaoying, Zhao, Chengguang, Yang, Lehe, Wang, Liangxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652895/
https://www.ncbi.nlm.nih.gov/pubmed/36371217
http://dx.doi.org/10.1186/s12967-022-03741-9