Cargando…

Aging beyond menopause selectively decreases CD8+ T cell numbers but enhances cytotoxic activity in the human endometrium

BACKGROUND: Regulation of endometrial (EM) CD8+ T cells, which provide protection through cell-mediated cytotoxicity, is essential for successful reproduction, and protection against sexually transmitted infections and potential tumors. We have previously demonstrated that EM CD8+ T cell cytotoxicit...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Zheng, Patel, Mickey V., Rodriguez-Garcia, Marta, Wira, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652910/
https://www.ncbi.nlm.nih.gov/pubmed/36371240
http://dx.doi.org/10.1186/s12979-022-00312-w