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Aging beyond menopause selectively decreases CD8+ T cell numbers but enhances cytotoxic activity in the human endometrium
BACKGROUND: Regulation of endometrial (EM) CD8+ T cells, which provide protection through cell-mediated cytotoxicity, is essential for successful reproduction, and protection against sexually transmitted infections and potential tumors. We have previously demonstrated that EM CD8+ T cell cytotoxicit...
Autores principales: | Shen, Zheng, Patel, Mickey V., Rodriguez-Garcia, Marta, Wira, Charles R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652910/ https://www.ncbi.nlm.nih.gov/pubmed/36371240 http://dx.doi.org/10.1186/s12979-022-00312-w |
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