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Combination of polythyleneimine regulating autophagy prodrug and Mdr1 siRNA for tumor multidrug resistance
Multidrug resistance (MDR) has been restricting the efficacy of chemotherapy, which mainly include pump resistance and non-pump resistance. In order to fight overall MDR, a novel targeted gene/drug co-deliver nano system is developed, which can suppress the drug efflux pumps and modulate autophagy t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652912/ https://www.ncbi.nlm.nih.gov/pubmed/36369077 http://dx.doi.org/10.1186/s12951-022-01689-y |