The H2A.Z-KDM1A complex promotes tumorigenesis by localizing in the nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC), originating from the bile ducts, is the second most common primary liver malignancy, and its incidence has recently increased. H2A.Z, a highly conserved H2A variant, is emerging as a key regulatory molecule in cancer. However, its underlying mechani...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Qi, Yongqiang, Xiong, Fei, Wang, Da, Wang, Bing, Chen, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652970/
https://www.ncbi.nlm.nih.gov/pubmed/36368958
http://dx.doi.org/10.1186/s12885-022-10279-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652970/
https://www.ncbi.nlm.nih.gov/pubmed/36368958
http://dx.doi.org/10.1186/s12885-022-10279-y

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