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Local Anesthetic Like Inhibition of the Cardiac Na(+) Channel Nav1.5 by Chloroquine and Hydroxychloroquine

INTRODUCTION: Chloroquine (CQ) and its derivate hydroxychloroquine (HCQ) are successfully deployed for different diseases beyond the prophylaxis and treatment of malaria. Both substances exhibit antiviral properties and have been proposed for prophylaxis and treatment of COVID-19 caused by SARS-CoV-...

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Detalles Bibliográficos
Autores principales: Hage, Axel, de Vries, Mathis, Leffler, Andreas, Stoetzer, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653037/
https://www.ncbi.nlm.nih.gov/pubmed/36385942
http://dx.doi.org/10.2147/JEP.S375349