Cargando…

TiDeTree: a Bayesian phylogenetic framework to estimate single-cell trees and population dynamic parameters from genetic lineage tracing data

The development of organisms and tissues is dictated by an elaborate balance between cell division, apoptosis and differentiation: the cell population dynamics. To quantify these dynamics, we propose a phylodynamic inference approach based on single-cell lineage recorder data. We developed a Bayesia...

Descripción completa

Detalles Bibliográficos
Autores principales: Seidel, Sophie, Stadler, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653226/
https://www.ncbi.nlm.nih.gov/pubmed/36350216
http://dx.doi.org/10.1098/rspb.2022.1844