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Structural perturbations of substrate binding and oxidation state changes in a lytic polysaccharide monooxygenase

LPMOs are enzymes which catalyse the oxidation of a C-H bond within polysaccharides, leading to their oxidative cleavage. To achieve this, LPMOs employ highly reactive oxidising intermediates, the generation of which is likely coupled to substrate binding to the enzyme. The nature of this coupling i...

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Detalles Bibliográficos
Autores principales: Walton, Paul H., Davies, Gideon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653361/
https://www.ncbi.nlm.nih.gov/pubmed/36208326
http://dx.doi.org/10.1007/s00775-022-01966-z