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Structural perturbations of substrate binding and oxidation state changes in a lytic polysaccharide monooxygenase
LPMOs are enzymes which catalyse the oxidation of a C-H bond within polysaccharides, leading to their oxidative cleavage. To achieve this, LPMOs employ highly reactive oxidising intermediates, the generation of which is likely coupled to substrate binding to the enzyme. The nature of this coupling i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653361/ https://www.ncbi.nlm.nih.gov/pubmed/36208326 http://dx.doi.org/10.1007/s00775-022-01966-z |