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Hypothermia evoked by stimulation of medial preoptic nucleus protects the brain in a mouse model of ischaemia

Therapeutic hypothermia at 32-34 °C during or after cerebral ischaemia is neuroprotective. However, peripheral cold sensor-triggered hypothermia is ineffective and evokes vigorous counteractive shivering thermogenesis and complications that are difficult to tolerate in awake patients. Here, we show...

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Detalles Bibliográficos
Autores principales: Zhang, Shuai, Zhang, Xinpei, Zhong, Haolin, Li, Xuanyi, Wu, Yujie, Ju, Jun, Liu, Bo, Zhang, Zhenyu, Yan, Hai, Wang, Yizheng, Song, Kun, Hou, Sheng-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653397/
https://www.ncbi.nlm.nih.gov/pubmed/36371436
http://dx.doi.org/10.1038/s41467-022-34735-2