Microfluidic live tracking and transcriptomics of cancer-immune cell doublets link intercellular proximity and gene regulation

Cell–cell communication and physical interactions play a vital role in cancer initiation, homeostasis, progression, and immune response. Here, we report a system that combines live capture of different cell types, co-incubation, time-lapse imaging, and gene expression profiling of doublets using a m...

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Detalles Bibliográficos
Autores principales: Flores, Bianca C. T., Chawla, Smriti, Ma, Ning, Sanada, Chad, Kujur, Praveen Kumar, Yeung, Rudy, Bellon, Margot B., Hukari, Kyle, Fowler, Brian, Lynch, Mark, Chinen, Ludmilla T. D., Ramalingam, Naveen, Sengupta, Debarka, Jeffrey, Stefanie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653407/
https://www.ncbi.nlm.nih.gov/pubmed/36371461
http://dx.doi.org/10.1038/s42003-022-04205-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653407/
https://www.ncbi.nlm.nih.gov/pubmed/36371461
http://dx.doi.org/10.1038/s42003-022-04205-y

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