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Microfluidic live tracking and transcriptomics of cancer-immune cell doublets link intercellular proximity and gene regulation
Cell–cell communication and physical interactions play a vital role in cancer initiation, homeostasis, progression, and immune response. Here, we report a system that combines live capture of different cell types, co-incubation, time-lapse imaging, and gene expression profiling of doublets using a m...
Autores principales: | Flores, Bianca C. T., Chawla, Smriti, Ma, Ning, Sanada, Chad, Kujur, Praveen Kumar, Yeung, Rudy, Bellon, Margot B., Hukari, Kyle, Fowler, Brian, Lynch, Mark, Chinen, Ludmilla T. D., Ramalingam, Naveen, Sengupta, Debarka, Jeffrey, Stefanie S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653407/ https://www.ncbi.nlm.nih.gov/pubmed/36371461 http://dx.doi.org/10.1038/s42003-022-04205-y |
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