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Structure-guided insights into potential function of novel genetic variants in the malaria vaccine candidate PfRh5
The recent stall in the global reduction of malaria deaths has made the development of a highly effective vaccine essential. A major challenge to developing an efficacious vaccine is the extensive diversity of Plasmodium falciparum antigens. While genetic diversity plays a major role in immune evasi...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653458/ https://www.ncbi.nlm.nih.gov/pubmed/36371450 http://dx.doi.org/10.1038/s41598-022-23929-9 |