Structure-guided insights into potential function of novel genetic variants in the malaria vaccine candidate PfRh5

The recent stall in the global reduction of malaria deaths has made the development of a highly effective vaccine essential. A major challenge to developing an efficacious vaccine is the extensive diversity of Plasmodium falciparum antigens. While genetic diversity plays a major role in immune evasi...

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Detalles Bibliográficos
Autores principales: Mangou, Khadidiatou, Moore, Adam J., Thiam, Laty Gaye, Ba, Aboubacar, Orfanó, Alessandra, Desamours, Ife, Ndegwa, Duncan Ndungu, Goodwin, Justin, Guo, Yicheng, Sheng, Zizhang, Patel, Saurabh D., Diallo, Fatoumata, Sene, Seynabou D., Pouye, Mariama N., Faye, Awa Thioub, Thiam, Alassane, Nunez, Vanessa, Diagne, Cheikh Tidiane, Sadio, Bacary Djilocalisse, Shapiro, Lawrence, Faye, Ousmane, Mbengue, Alassane, Bei, Amy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653458/
https://www.ncbi.nlm.nih.gov/pubmed/36371450
http://dx.doi.org/10.1038/s41598-022-23929-9

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