Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica

Engineering microbes to produce plant-derived natural products provides an alternate solution to obtain bioactive products. Here we report a systematic approach to sequentially identify the rate-limiting steps and improve the biosynthesis of the cannabinoid precursor olivetolic acid (OLA) in Yarrowi...

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Detalles Bibliográficos
Autores principales: Ma, Jingbo, Gu, Yang, Xu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653464/
https://www.ncbi.nlm.nih.gov/pubmed/36371560
http://dx.doi.org/10.1038/s42003-022-04202-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9653464/
https://www.ncbi.nlm.nih.gov/pubmed/36371560
http://dx.doi.org/10.1038/s42003-022-04202-1

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